Specialist literature has extensively analyzed the concept of memory in Plato, Aristotle, the Stoa, and the Garden, revealing a theoretical continuity between Plato’s dialogues and Aristotle’s works, as well as between the Hellenistic schools and their Platonic and Aristotelian antecedents. This article aims to address an issue that has not yet been thoroughly examined: how Antiochus of Ascalon defines memory within the epistemological debate of Cicero’s Academici, and how Cicero polemically responds to Antiochus’ Stoic conception of mneme.